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Part il molecular biotechnology of microbial systems 331 contents chapter 11 nucleic acids as therapeutic agents 426 antisense rna 426 antisense oligonucleotides 428.
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Rnas rather than a library of large, bulky proteins. the ease of cas9 targeting, its high efficiency as a site-specific nuclease, and the possibility for highly.
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(2’–o-me) or 2’–o-methoxyethyl-oligonucleotides (2’– o-moe) [63], peptide nucleic acids (pna) [64], fluorine derivatives (fana and 2’-f) and other.
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Components of plants (cellulose), animals (chitin), and nucleic acids (dna, rna). however, greater variation in oligosac-charide structure is exploited by nature.
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